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Our Services |
We provide consulting services in computer assisted drug design and custom programming of scientific applications. Data mining and visualization are our strengths Our consulting services are flexible, from punctual projects to strategic guidance in the drug design arena. We have a comprehensive view of the full drug discovery cycle that allows our customers to have a partner that not only understands the tools but also is familiar with the needs of a drug discovery program. Pharmacophore based, Docking, Virtual Screening Screening Library design: focused, fragment In-silico toxicology and ADME prediction Scientific software application development Infrastructure: Software, hardware selection |
EXAMPLES OF OUR WORK INCLUDE: Developed a series of homology models for a panel of related enzymes to identify pan selective inhibitors. In collaboration with medicinal chemists, docked candidate structures and selected most promising scaffolds for follow-up. Aided company in the selection of software to establish a molecular modeling facility. From delineating requirements to participation in negotiations with vendors, to the training of staff we participated in the entire facility build up process. Carried out virtual screening for a kinase target with the ultimate purpose of improving the activity and pharmacokinetic profile of leads identified by HTS. Trained personnel in the techniques for lead hopping when no structural information on the target was available. |